Clinical, social and psychological factors of the effectiveness of remission in alcohol dependence

Clinical, social and psychological factors of the effectiveness of remission in alcohol dependence

 

Authors

 

A.I. Mandel

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russian Federation

I.V. Voevodin

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russian Federation

R.I. Bedarev

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russian Federation

N.A. Bokhan

Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russian Federation; Federal State Budgetary Educational Institution of Higher Education “Siberian State Medical University” of the Ministry of Health of the Russian Federation, Tomsk, Russian Federation

 

https://doi.org/10.26617/1810-3111-2025-2(127)-45-52

 

Journal: Siberian Herald of Psychiatry and Addiction Psychiatry. 2025; 2 (127):  45-52.

 

Abstract

Background. Alcohol dependence is one of the most socially significant diseases and is a multi-aspect problem in its manifestations and consequences. The success of intervention in conditions of complicated clinical pictures and the course of alcoholism is associated with personalization of therapy, which allows for complete reduction of manifestations of withdrawal, comorbid emotional disorders and craving. In this regard, an urgent task is to study the factors influencing the effectiveness of remission formation. Objective: to study clinical, social, psychological factors influencing the effectiveness of remission formation in patients with alcohol dependence. Materials. The study included male patients (n=59) with the diagnosis of: Mental and behavioral disorders due to psychoactive substance use (ICD-10 codes F10-F19), aged 32 to 67 years (mean age 48 [43; 55] years). The examination was conducted at two control points ‒ after the patient came out of the abstinence state and at the time of discharge from the hospital. Methods: clinical-psychopathological, clinical-dynamic, psychometric, experimental-psychological, sociodemographic, statistical. Using a comparative analysis of the obtained data, potential factors of the intervention effectiveness were studied. Results: the risk group for unstable formation of remission in alcohol dependence included patients with an exacerbation of characterological traits of rigidity, conflict, with a reduced ability to rationally assess stressful situations (including those provoking the use of alcohol), prone to a pessimistic prognosis, with low compliance and impaired family adaptation. Clinical manifestations in these patients were characterized by a greater severity of the post-withdrawal state, difficulties in forming attitudes towards sobriety during treatment, psychopathic disorders in the form of aggressiveness, anger, deceit, manifestations of hysterical depression, overestimation of their importance, lack of empathy. The identified features should be taken into account at the stage of planning personalized therapy and during its implementation.

 

Keywords: alcohol dependence, remission, therapy effectiveness, clinical, social, psychological factors.

 

Article (pdf)

 

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Materials  

 

For citation: Mandel A.I., Voevodin I.V., Bedarev R.I., Bokhan N.A. Clinical, social and psychological factors of the effectiveness of remission in alcohol dependence. Sibirskii Vestnik Psikhiatrii i Narkologii.2025; 2 (127): 45-52. https://doi.org/10.26617/1810-3111-2025-2(127)-45-52

 

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