Clinical aspects of behavioral dysregulation in individuals with schizophrenia who have committed socially dangerous acts
Authors
O.A. Makushkina
FSBI “V.P. Serbsky National Medical Research Center of Psychiatry and Narcology” of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
A.V. Frolova
FSBI “V.P. Serbsky National Medical Research Center of Psychiatry and Narcology” of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
E.V. Leurda
FSBI “V.P. Serbsky National Medical Research Center of Psychiatry and Narcology” of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
N.G. Sharabidze
FSBI “V.P. Serbsky National Medical Research Center of Psychiatry and Narcology” of the Ministry of Health of the Russian Federation, Moscow, Russian Federation
https://doi.org/10.26617/1810-3111-2024-4(125)-36-46
Journal: Siberian Herald of Psychiatry and Addiction Psychiatry. 2024; 4 (125): 36-46.
Abstract
Background.The social danger of persons with mental disorders is characterized by a high prevalence of serious offenses and a significant rate of their repetition. At the same time, the problem of behavioral dysregulation in this category of patients with determination of its genesis and characteristics for prevention of repeated offenses has not been previously studied. Objective: to study the genesis of behavioral dysregulation in patients with schizophrenia who have committed socially dangerous acts (SDA). Materials. An observational descriptive study was conducted on the basis of State Budgetary Healthcare Institution of the Moscow Region “Psychiatric Hospital No. 2 named after V.I. Yakovenko”. The examined patients (n=65) aged 18-60 years (mean age – 38±10 years) with behavioral dysregulation, diagnosed with schizophrenia (F20) according to ICD-10, undergoing compulsory treatment after committing SDA. Methods: clinical-psychopathological, psychometric (using the Brief Psychiatric Rating Scale, the Structured Assessment of the Risk of Dangerous Behavior) method. Collection, adjustment, and systematization of the initial information were carried out in Microsoft Office Excel 2019. Statistical analysis was performed using IBM SPSS Statistics v.26. Results. The characteristics of this contingent were as follows: high prevalence of hereditary burden and pathology of early development, repeated suffering from exogenous harm leading to cerebro-organic damage; predominance in the premorbid period of emotionally unstable character traits with an asocial orientation of behavior, early onset of psychoactive substance use. The psychological characteristics of most respondents were affective rigidity, external locus of control with predominantly externally accusing methods of response, pronounced egocentrism, and inflated self-esteem. Common clinical characteristics of the disease process included: adolescence at the onset of the disease, a long continuous course with an increase in negative symptoms in the form of emotional inadequacy, paradoxical response, opposition, lack of empathy, rudeness of affective outbursts, combined with a pronounced disturbance of critical and prognostic abilities; the addition of comorbid addiction to alcohol/drugs. The predominance of three variants of psychopathological mechanisms for committing the delinquency was determined: a positive-psychotic mechanism with delusional motivation, a negative-personal mechanism of emotional uncontrollability, a negative-personal mechanism with the dominance of pathology of drives. These mechanisms were characterized by a specific dysregulation of patients' behavior with differences in disturbances of its motivation, productivity, arbitrariness and flexibility. Conclusion. The results of the study can be used to develop complex models of delinquency; algorithms for assessing the risk of its relapse; defining the prevention strategy based on the principles of personalized medicine and interdisciplinary interaction.
Keywords: schizophrenia, clinical features, behavioral dysregulation, social danger.
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Materials
For citation: Makushkina O.A., Frolova A.V., Leurda E.V., Sharabidze N.G. Clinical aspects of behavioral dysregulation in individuals with schizophrenia who have committed socially dangerous acts. Siberian Herald of Psychiatry and Addiction Psychiatry.2024; 4 (125): 36-46. https://doi.org/10.26617/1810-3111-2024-4(125)-36-46
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