Связь между болезнью Альцгеймера и кожными заболеваниями (исследование и анализ литературы)

Связь между болезнью Альцгеймера и кожными заболеваниями (исследование и анализ литературы)

 

Авторы

 

А.П. Сиденкова

ФГБОУ ВО «Уральский государственный медицинский университет» Минздрава России, Екатеринбург, Россия

Н.Ю. Важенина

Центр косметологии и пластической медицины им. С.В. Нудельмана, Екатеринбург, Россия

 

https://doi.org/10.26617/1810-3111-2026-1(130)-116-130

 

Журнал:Сибирский вестник психиатрии и наркологии. 2026; 1(130): 116-130.

 

Реферат

Рост удельной доли лиц старших возрастных групп в населении ведет к увеличению распространенности возраст-ассоциированных заболеваний, среди которых одно из лидирующих мест занимает болезнь Альцгеймера (БА). Частая коморбидность БА с поражением кожными заболеваниями, единое эмбриотическое происхождение эпидермального слоя кожи и головного мозга позволяют предположить участие эпидермиса в наличие общих патогенетических звеньев в их формировании. Цель: на основе анализа научных публикаций установить связь между кожными заболеваниями эпидермальной локализации и возникновением БА для дальнейшей разработки её неинвазивной диагностики. Материал и методы. Материалом исследования послужили научные публикации зарубежных и отечественных авторов по теме работы. Применен общенаучный метод: объективный анализ современных научных источников по проблеме исследования, обобщение, сравнение, систематизация теоретических данных о когнитивном континууме. Информационный поиск проводился по ключевым словам. Изменения в эпидермальном слое кожи у пациентов с БА отличаются от нормальных возраст-ассоциированных изменений, происходящих в эпидермисе. Периферические ткани единой эмбриональной закладки с головным мозгом (щечный и буккальный эпителий, эпидермальный слой кожи) являются потенциальными неинвазивными биомаркерами БА.

 

Ключевые слова: болезнь Альцгеймера, деменция, когнитивное расстройство, кожа, эпидермальный слой кожи, эпидермис, буккальный эпителий, эктодерма.

 

Статья (pdf)

 

Связь с автором

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Дополнительные материалы

Для цитирования:Сиденкова А.П.,Важенина Н.Ю. Связь между болезнью Альцгеймера и кожными заболеваниями (исследование и анализ литературы). Сибирский вестник психиатрии и наркологии. 2026. № 1 (130). С. 116-130. https://doi.org/10.26617/1810-3111-2026-1(130)-116-130

 

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